Description

2-[(E)-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethenyl]Pyridine is a high-value, versatile boronic ester derivative featuring a pyridine moiety. This compound is a critical building block in modern synthetic organic chemistry, enabling the formation of complex molecular architectures through cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing biphenyl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the pyridine-boronate functionality allows for efficient structure-activity relationship (SAR) studies.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated pyridine-based ligands for transition metal catalysis.
• Material Science Research: Utilized in the development of metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and other functional polymeric materials.
• Chemical Biology Probes: Acts as a handle for bioconjugation and the synthesis of molecular probes for imaging and diagnostic applications.

Basic Information

Product Name	2-[(E)-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethenyl]Pyridine
CAS No.	161395-83-1
Molecular Formula	C15H22BNO2
Molecular Weight	259.15 g/mol
Synonyms	(E)-2-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)pyridine; 2-[(E)-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl]pyridine; 2-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)ethenyl)pyridine; Pyridine, 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethenyl]-, (E)-; 2-Vinylpyridine pinacol boronic ester; Trans-2-(2-Pyridyl)vinylboronic acid pinacol ester; (E)-2-(2-Pyridylvinyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-[(E)-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethenyl]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance in sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (E/Z Ratio by HPLC)	≥ 98:2 (E:Z)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.