Description

1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[(1E)-2-(2-Thienyl)Ethenyl]- is a high-purity, functionalized organoboron reagent, specifically a pinacol-protected vinylboronate ester. This compound matters as a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation through cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for introducing the 2-(2-thienyl)ethenyl moiety into complex molecules, widely used in pharmaceutical and materials synthesis.
• Pharmaceutical Intermediate: Serves as a versatile precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing heterocyclic thiophene units.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the thienylvinyl group imparts specific biological activity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a monomer or intermediate in the production of conjugated polymers and small molecules for electronic and optoelectronic devices.
• Material Science Research: Employed in the creation of novel organic semiconductors, liquid crystals, and functional polymers.
• Chemical Biology & Proteomics: Can be utilized as a tagging or bioconjugation reagent due to the reactivity of the boronate ester and the vinyl group.

Basic Information

Item	Detail
Product Name	1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[(1E)-2-(2-Thienyl)Ethenyl]-
CAS No.	161395-82-0
Molecular Formula	C12H19BO2S
Molecular Weight	238.16 g/mol
Synonyms	(E)-2-(2-(Thiophen-2-yl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-[(1E)-2-(2-Thienyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-2-(2-Thienylvinyl)pinacolborane; trans-2-(2-Thienylvinyl)pinacol boronate; 2-(2-Thienylvinyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; Pinacol (E)-2-(2-thienylvinyl)boronate; Thiophene-2-vinylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[(1E)-2-(2-Thienyl)Ethenyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z ratio by HPLC)	≥ 98:2 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.