Description

(2,2,2-Trifluoro-1-Methylethyl)Benzene is a high-purity fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a trifluoromethylated ethyl side chain, provides valuable properties for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fluorinated component in the synthesis of specialty materials for electronic displays and organic light-emitting diodes.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to impart unique solubility, thermal stability, and surface properties to high-performance polymers.
• Catalyst & Ligand Development: Utilized in the design of novel fluorinated ligands for catalysis in asymmetric synthesis and cross-coupling reactions.
• Organic Synthesis Building Block: Provides a versatile aromatic core for further functionalization in complex multi-step synthetic routes.

Basic Information

Product Name	(2,2,2-Trifluoro-1-Methylethyl)Benzene
CAS No.	161361-16-6
Molecular Formula	C9H9F3
Molecular Weight	174.16 g/mol
Synonyms	1-Methyl-2,2,2-trifluoroethylbenzene; α,α,α-Trifluoroethylbenzene; (1,1,1-Trifluoro-2-phenylethane); Benzene, (2,2,2-trifluoro-1-methylethyl)-; 2-Phenyl-1,1,1-trifluoropropane; (2,2,2-Trifluoroethyl)benzene (common misnomer, verify structure); α-Trifluoromethylphenylethane
EINECS	Contact for details

Quality Control

Every batch of (2,2,2-Trifluoro-1-Methylethyl)Benzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is 2-8°C for long-term stability, though the material is typically stable at controlled room temperature (15-25°C) for shorter periods.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.