Description

2-Butyl-1,3,2-Dioxaborolane-4S,5S-Dicarboxylic Acid Bis(Dimethylamide) is a chiral, cyclic boronic ester derivative valued for its role as a versatile intermediate and ligand in asymmetric synthesis. This compound matters for its ability to facilitate stereoselective transformations, particularly in the construction of complex molecules with high enantiomeric purity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. The product is supplied with a CAS number of 161344-84-9.

Application

• As a chiral ligand or catalyst in asymmetric synthesis, including Suzuki-Miyaura cross-coupling reactions.
• As a key synthetic intermediate in the research and development of novel pharmaceutical compounds.
• For the preparation of boron-containing building blocks used in medicinal chemistry and drug discovery.
• In the synthesis of advanced materials where precise stereochemistry is required.
• As a reagent in academic and industrial research for exploring new catalytic methodologies.

Basic Information

Product Name	2-Butyl-1,3,2-Dioxaborolane-4S,5S-Dicarboxylic Acid Bis(Dimethylamide)
CAS No.	161344-84-9
Molecular Formula	C14H27BN2O4
Molecular Weight	298.19 g/mol
Synonyms	(4S,5S)-2-Butyl-1,3,2-dioxaborolane-4,5-dicarboxylic acid bis(dimethylamide); (S,S)-2-Butyl-1,3,2-dioxaborolane-4,5-dicarboxylic Acid Bis(N,N-dimethylamide); Chiral Dioxaborolane Bis(Dimethylamide); (4S,5S)-2-Butyl-4,5-bis(dimethylcarbamoyl)-1,3,2-dioxaborolane; Boronic Ester Bisamide; 161344-84-9
EINECS	Contact for details

Quality Control

Our 2-Butyl-1,3,2-Dioxaborolane-4S,5S-Dicarboxylic Acid Bis(Dimethylamide) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.