Description

1H-Inden-4-Ol,7-Fluoro-2,3-Dihydro-(9Ci) is a high-purity fluorinated indanol derivative, a key chiral building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex pharmacologically active molecules with high stereochemical fidelity. This compound is critically needed by research institutions and pharmaceutical development teams working on novel therapeutic agents, particularly in central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for CNS-targeting drugs.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to introduce the indanol moiety with defined stereochemistry.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Ligand and Catalyst Development: Acts as a backbone for creating novel chiral ligands and organocatalysts used in fine chemical manufacturing.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	1H-Inden-4-Ol,7-Fluoro-2,3-Dihydro-(9Ci)
CAS No.	161178-24-1
Molecular Formula	C9H9FO
Molecular Weight	152.16 g/mol
Synonyms	7-Fluoro-2,3-dihydro-1H-inden-4-ol; 7-Fluoro-2,3-dihydro-4-hydroxyindane; 4-Hydroxy-7-fluoroindane; 7-Fluoroindan-4-ol; (7-Fluoro-2,3-dihydro-1H-inden-4-yl)oxy; 161178-24-1; 4-Indanol, 7-fluoro-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our production of 1H-Inden-4-Ol,7-Fluoro-2,3-Dihydro-(9Ci) adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP compliance for pharmaceutical development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.