Description

2,3:5,6-Di-o-Isopropylidene-4-(Tetrahydropyran-2-Yl)-Myo-Inositol CAS NO 161003-28-7 is a sophisticated, protected myo-inositol derivative, a key chiral building block in organic synthesis. This compound matters for its role in constructing complex bioactive molecules, offering precise stereochemical control that is critical for pharmaceutical efficacy. It is primarily needed by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel therapeutics and advanced intermediates.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of phosphatidylinositol (PI) derivatives and inositol phosphate signaling molecules.
• Glycobiology Research: Used in the preparation of complex carbohydrate analogs and glycosidase inhibitors for biochemical studies.
• Nucleoside & Nucleotide Chemistry: Serves as a protected scaffold for the development of novel nucleoside analogs with potential antiviral or anticancer activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to introduce the myo-inositol core structure.
• Chemical Biology Probe Development: Utilized to create labeled or modified inositols for studying cellular signaling pathways.
• Process Chemistry: Acts as a high-value intermediate in the kilo-lab and pilot-scale production of target active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2,3:5,6-Di-o-Isopropylidene-4-(Tetrahydropyran-2-Yl)-Myo-Inositol
CAS No.	161003-28-7
Molecular Formula	C17H28O7
Molecular Weight	344.40 g/mol
Synonyms	4-(Tetrahydropyran-2-yl)-1,2:5,6-di-O-isopropylidene-myo-inositol; 1,2:5,6-Di-O-isopropylidene-4-O-(tetrahydro-2H-pyran-2-yl)-myo-inositol; 4-THP-Protected DIP-myo-inositol; 4-(THP)-1,2:5,6-di-O-isopropylidene-myo-inositol; myo-Inositol, 4-(tetrahydro-2H-pyran-2-yl)-, 1,2:5,6-bis-O-(1-methylethylidene)-; 4-THP-DIP-Inositol; Protected myo-Inositol derivative; CAS 161003-28-7
EINECS	Contact for details

Quality Control

Our 2,3:5,6-Di-o-Isopropylidene-4-(Tetrahydropyran-2-Yl)-Myo-Inositol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccant packs.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.