Description

2-(4-Fluoro-Phenyl)-[1,3,2]Dioxaborolane is a high-purity organoboron reagent, specifically a cyclic boronic ester, valued for its stability and reactivity in advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical manufacturing.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key arylboron reagent for forming carbon-carbon bonds between aryl halides and this fluorinated phenylboronate ester.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Compound Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides where the fluorine moiety enhances biological activity.
• Materials Science & OLED Research: Acts as a precursor for creating fluorinated organic electronic materials, such as charge-transport layers in organic light-emitting diodes (OLEDs).
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for imaging and diagnostic applications.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-[1,3,2]Dioxaborolane
CAS No.	160874-85-1
Molecular Formula	C8H8BFO2
Molecular Weight	165.96 g/mol
Synonyms	4-Fluorophenylboronic acid 1,3,2-dioxaborolane ester; 2-(4-Fluorophenyl)-1,3,2-dioxaborolane; 4-Fluorophenylboronic acid cyclic ester with ethylene glycol; 4-Fluorophenyl-1,3,2-dioxaborolane; 4-Fluorophenylboronate ethylene ester; (4-Fluorophenyl)-1,3,2-dioxaborolane; 4-Fluorophenyl-B-dihydroxyborane cyclic ethylene ester; 2-(p-Fluorophenyl)-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Phenyl)-[1,3,2]Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤3.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.