Description

1H-Pyrrolizine-1-Carboxaldehyde, 2,3,5,7A-Tetrahydro-5-Oxo-, (1S-Cis)- (9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused pyrrolizine core with an aldehyde functional group makes it a versatile precursor for constructing complex nitrogen-containing molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of potential drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the construction of novel heterocyclic pesticides and herbicides, leveraging its complex nitrogen-based scaffold.
• Academic & Contract Research: Serves as a specialized starting material in university laboratories and CROs (Contract Research Organizations) for methodological studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Process Chemistry Development: Utilized for scaling up synthetic routes from milligram to kilogram scale in pilot plants, requiring consistent high purity.

Basic Information

Product Name	1H-Pyrrolizine-1-Carboxaldehyde, 2,3,5,7A-Tetrahydro-5-Oxo-, (1S-Cis)- (9Ci)
CAS No.	160724-85-6
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	(1S,7aS)-2,3,5,7a-Tetrahydro-1H-pyrrolizine-1-carboxaldehyde 5-oxide; (1S-cis)-2,3,5,7a-Tetrahydro-5-oxo-1H-pyrrolizine-1-carboxaldehyde; 1H-Pyrrolizine-1-carboxaldehyde, 2,3,5,7a-tetrahydro-5-oxo-, (1S-cis)-; (1S,7aR)-Hexahydro-1H-pyrrolizin-1-carbaldehyde 5-oxide; 1-Pyrrolizinecarboxaldehyde, 2,3,5,7a-tetrahydro-5-oxo-, (1S-cis)-; L-Proline aldehyde derivative
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolizine-1-Carboxaldehyde, 2,3,5,7A-Tetrahydro-5-Oxo-, (1S-Cis)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and during aliquoting to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.