Description

6-o-Trityl-D-Mannopyranose is a protected carbohydrate derivative, specifically a trityl ether of D-mannose, widely used as a key synthetic intermediate in organic and medicinal chemistry. Its primary value lies in providing a robust, acid-labile protecting group for the primary hydroxyl position, enabling selective functionalization and complex oligosaccharide assembly. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel glycosides, glycoconjugates, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of complex carbohydrate-based drugs, antiviral agents, and vaccine adjuvants.
• Glycochemistry Research: Used in the stepwise synthesis of oligosaccharides and glycoconjugates for biological studies and drug discovery.
• Chemical Biology Probes: Serves as a precursor for labeled mannose derivatives used in metabolic labeling and imaging studies.
• Process Development: Employed in the scale-up and optimization of synthetic routes for carbohydrate-active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Intermediate for producing specialty surfactants, chiral ligands, and other high-value mannose-derived compounds.

Basic Information

Item	Detail
Product Name	6-o-Trityl-D-Mannopyranose
CAS No.	160712-27-6
Molecular Formula	C25H26O6
Molecular Weight	422.47 g/mol
Synonyms	1,2:3,4-Di-O-isopropylidene-6-O-trityl-α-D-mannopyranose; 6-O-Triphenylmethyl-1,2:3,4-di-O-isopropylidene-α-D-mannopyranose; 6-O-Trityl-1,2:3,4-di-O-isopropylidene-α-D-mannopyranose; 6-O-Trityl-D-mannose diacetonide; α-D-Mannopyranose, 6-O-trityl-, 1,2:3,4-bis-O-(1-methylethylidene)-; Trityl-D-mannose diacetonide
EINECS	Contact for details

Quality Control

Our 6-o-Trityl-D-Mannopyranose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and optical rotation measurement to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	-15° to -20° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.