Description

(2S)-3-Amino-1,1,1-trifluoro-2-propanol is a high-value, chiral fluorinated amino alcohol building block. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where its trifluoromethyl group and stereochemistry impart desirable metabolic stability and biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides that leverage fluorine's properties for enhanced efficacy and environmental profile.
• Ligand and Catalyst Preparation: Used in the synthesis of chiral ligands for asymmetric catalysis and metal complexes.
• Peptidomimetics Research: Incorporated into peptide backbones to enhance stability against enzymatic degradation in drug discovery.
• Fluorinated Material Science: Monomer or precursor for specialty polymers and advanced materials with unique surface properties.
• Chemical Biology Probes: Serves as a handle for introducing fluorine atoms into biomolecules for NMR studies and mechanistic investigations.

Basic Information

Item	Detail
Product Name	(2S)-3-Amino-1,1,1-trifluoro-2-propanol
CAS No.	160706-71-8
Molecular Formula	C3H6F3NO
Molecular Weight	129.08 g/mol
Synonyms	(S)-3-Amino-1,1,1-trifluoro-2-propanol; (S)-3-Amino-1,1,1-trifluoropropan-2-ol; (S)-1,1,1-Trifluoro-3-amino-2-propanol; (2S)-1,1,1-Trifluoro-3-aminopropan-2-ol; (S)-3-Amino-2-hydroxy-1,1,1-trifluoropropane; (S)-Trifluoromethyl alaninol; (S)-TFA; (S)-3-Amino-1,1,1-trifluoro-isopropanol
EINECS	Contact for details

Quality Control

Our (2S)-3-Amino-1,1,1-trifluoro-2-propanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with full specification data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.