Description

Cholesteryl Hydroxystearate is a high-purity, synthetic cholesterol derivative where a hydroxystearic acid moiety is esterified to the cholesterol backbone. This specific molecular architecture makes it a valuable functional ingredient and intermediate, offering unique properties of biocompatibility and amphiphilicity. It is primarily utilized in the pharmaceutical, cosmetic, and advanced material sectors for its ability to modify rheology, stabilize formulations, and act as a building block for liquid crystals and drug delivery systems. Global industries seeking innovative excipients and specialty additives will find this compound of significant technical interest.

Application

• Pharmaceutical Excipient: Used as a stabilizer, emulsifier, or matrix component in topical formulations, ointments, and controlled-release drug delivery systems.
• Cosmetic & Personal Care: Functions as a thickening agent, emollient, and stabilizer in creams, lotions, lipsticks, and other skincare products for improved texture and stability.
• Liquid Crystal Materials: Serves as a key chiral dopant or component in the research and development of thermotropic and lyotropic liquid crystals for display and sensor technologies.
• Biomaterial Research: Employed as a synthetic analog in studies of lipid membranes, cholesterol metabolism, and the development of biocompatible coatings.
• Lipid Nanoparticle (LNP) Formulation: Investigated as a functional lipid component to modulate the properties and performance of LNPs used in mRNA and other nucleic acid delivery.
• Laboratory Reagent: Used as a high-purity standard or intermediate in organic synthesis and analytical chemistry research.

Basic Information

Product Name	Cholesteryl Hydroxystearate
CAS No.	160525-18-8
Molecular Formula	C₄₅H₈₀O₃
Molecular Weight	669.1 g/mol
Synonyms	Cholest-5-en-3β-yl 12-hydroxyoctadecanoate; 12-Hydroxyoctadecanoic acid cholesteryl ester; Cholesterol 12-hydroxystearate; Hydroxystearic Acid Cholesteryl Ester; Cholesteryl 12-hydroxystearate
EINECS	Contact for details

Quality Control

Our Cholesteryl Hydroxystearate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and physical characteristics. While not certified as USP or Ph. Eur., our production adheres to cGMP principles suitable for pharmaceutical and cosmetic R&D applications, ensuring reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using an inert atmosphere to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.