Description

5-(4-Bromophenyl)-2,4-Dihydro-2-Methyl-3H-Pyrazol-3-One is a versatile brominated pyrazolone derivative, a key heterocyclic building block prized for its unique chemical reactivity. This compound is essential for researchers and manufacturers requiring a high-purity intermediate to introduce specific molecular frameworks into more complex structures. It is primarily utilized in the development of advanced pharmaceutical compounds, agrochemicals, and functional materials where its specific bromophenyl substitution pattern is critical.

Application

• Pharmaceutical Intermediate: A crucial synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a foundational scaffold for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazolone core.
• Material Science Precursor: Used in the synthesis of organic ligands for metal-organic frameworks (MOFs) and other advanced functional materials due to its potential chelating properties.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other organic transformations to construct complex molecules for various R&D applications.
• Dye & Pigment Intermediate: Acts as a precursor in the production of specialized dyes and pigments, where the bromine atom facilitates further chemical modifications.

Basic Information

Product Name	5-(4-Bromophenyl)-2,4-Dihydro-2-Methyl-3H-Pyrazol-3-One
CAS No.	160377-46-8
Molecular Formula	C10H9BrN2O
Molecular Weight	253.10 g/mol
Synonyms	5-(4-Bromophenyl)-3-methyl-1H-pyrazol-3(2H)-one; 5-(p-Bromophenyl)-2,4-dihydro-2-methyl-3H-pyrazol-3-one; 3-Methyl-5-(4-bromophenyl)-2-pyrazolin-5-one; 4-Bromo-α-methylpyrazolone; 1-Methyl-3-(4-bromophenyl)-5-pyrazolone; p-Bromophenyl methyl pyrazolone
EINECS	Contact for details

Quality Control

Our 5-(4-Bromophenyl)-2,4-Dihydro-2-Methyl-3H-Pyrazol-3-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.