Description

1-(1-Bromoethyl)-3,5-Bis-Trifluoromethyl-Benzene is a high-value, multi-functional aromatic building block characterized by its reactive bromoethyl side chain and electron-deficient bis-trifluoromethylphenyl core. This compound is essential for advanced organic synthesis, particularly in the development of complex molecules where the introduction of fluorinated aromatic systems is required. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing active ingredients and functional monomers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, where the trifluoromethyl groups enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides, leveraging the lipophilicity and stability imparted by the fluorinated aromatic ring.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, including palladium-catalyzed cross-coupling reactions.
• Advanced Material Monomer: Employed in the research and production of specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Chemical Research & Development: A versatile reagent for introducing the 3,5-bis(trifluoromethyl)benzyl moiety into more complex molecular architectures via further functionalization of the bromoethyl group.

Basic Information

Product Name	1-(1-Bromoethyl)-3,5-Bis-Trifluoromethyl-Benzene
CAS No.	160376-84-1
Molecular Formula	C11H7BrF6
Molecular Weight	333.07 g/mol
Synonyms	1-(1-Bromoethyl)-3,5-bis(trifluoromethyl)benzene; α-Bromoethyl-3,5-bis(trifluoromethyl)benzene; (1-Bromoethyl)-3,5-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)-α-bromoethylbenzene; 1-Bromo-1-(3,5-bis(trifluoromethyl)phenyl)ethane; [3,5-Bis(trifluoromethyl)phenyl]bromoethane
EINECS	Contact for details

Quality Control

Every batch of 1-(1-Bromoethyl)-3,5-Bis-Trifluoromethyl-Benzene is manufactured and tested under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly sealed in a dry environment to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.