Description

6-(2,2,2-Trifluoro-Ethoxy)-Pyridine-3-Carbaldehyde is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoroethoxy side chain and an aldehyde functional group, makes it indispensable for introducing specific fluorine-containing motifs into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the trifluoroethoxy group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and for developing novel organometallic complexes.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or polymers with tailored electronic properties, due to its fluorine content.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	6-(2,2,2-Trifluoro-Ethoxy)-Pyridine-3-Carbaldehyde
CAS No.	159981-19-8
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	3-Formyl-6-(2,2,2-trifluoroethoxy)pyridine; 6-(2,2,2-Trifluoroethoxy)nicotinaldehyde; 6-(2,2,2-Trifluoroethoxy)pyridine-3-carboxaldehyde; Pyridine-3-carboxaldehyde, 6-(2,2,2-trifluoroethoxy)-; 159981-19-8; 6-(Trifluoroethoxy)pyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 6-(2,2,2-Trifluoro-Ethoxy)-Pyridine-3-Carbaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.