Description

Methyl-2-Deoxy-2-(Trifluoromethyl)-α-D-Arabinofuranoside Diacetate is a specialized fluorinated carbohydrate derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in the unique combination of the arabinofuranoside scaffold with a strategically positioned trifluoromethyl group, which is highly sought after for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the development of novel nucleoside analogs, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents, where the trifluoromethyl group enhances metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the fluorine atom's ability to improve biological activity and environmental persistence.
• Glycobiology & Medicinal Chemistry: Serves as a versatile scaffold for constructing complex glycoconjugates and probing carbohydrate-protein interactions.
• Process Chemistry & Scale-up: Employed in route development and optimization for the commercial production of fluorinated active pharmaceutical ingredients (APIs).
• Chemical Biology Tool: Utilized in the synthesis of activity-based probes and labeled compounds for studying enzymatic mechanisms and metabolic pathways.
• Material Science Research: Investigated as a monomer or modifier for creating specialty polymers with unique surface properties and stability.

Basic Information

Product Name	Methyl-2-Deoxy-2-(Trifluoromethyl)-α-D-Arabinofuranoside Diacetate
CAS No.	159945-02-5
Molecular Formula	C₁₂H₁₅F₃O₇
Molecular Weight	328.24 g/mol
Synonyms	Methyl 2-deoxy-2-(trifluoromethyl)-α-D-arabinofuranoside diacetate; 1,2,3-Tri-O-acetyl-5-deoxy-5-C-trifluoromethyl-α-D-arabinofuranose; 5-Deoxy-5-C-trifluoromethyl-1,2,3-tri-O-acetyl-α-D-arabinofuranose; Methyl 5-deoxy-5-C-trifluoromethyl-2,3-di-O-acetyl-α-D-arabinofuranoside; α-D-Arabinofuranoside, methyl 2-deoxy-2-(trifluoromethyl)-, diacetate
EINECS	Contact for details

Quality Control

Our Methyl-2-Deoxy-2-(Trifluoromethyl)-α-D-Arabinofuranoside Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.