Description

Methyl-2-C-(Trifluoromethyl)-α-D-Ribofuranoside-3,5-Diacetate is a high-purity, fluorinated ribofuranoside derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in the precise introduction of a trifluoromethyl group and protected sugar scaffold, enabling the development of novel compounds with enhanced metabolic stability and bioavailability. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of nucleoside analogs, antiviral agents, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of novel nucleoside analogs and antiviral/antitumor drug candidates.
• Agrochemical Research: Building block for developing new fluorinated pesticides and herbicides with improved activity and environmental profiles.
• Chemical Biology: Probe or substrate in enzymatic studies and metabolic pathway investigations due to its modified sugar structure.
• Process Chemistry: Used in route development and scale-up for the production of complex fluorinated organic molecules.
• Academic & R&D: Valuable reagent for methodological research in carbohydrate and fluorine chemistry.

Basic Information

Product Name	Methyl-2-C-(Trifluoromethyl)-α-D-Ribofuranoside-3,5-Diacetate
CAS No.	159944-99-7
Molecular Formula	C11H15F3O7
Molecular Weight	316.23 g/mol
Synonyms	Methyl 2-C-(Trifluoromethyl)-α-D-ribofuranoside 3,5-diacetate; 1-O-Methyl-2-C-trifluoromethyl-α-D-ribofuranose 3,5-diacetate; 2-C-Trifluoromethyl-1-O-methyl-α-D-ribofuranose 3,5-diacetate; α-D-Ribofuranoside, methyl 2-C-(trifluoromethyl)-, 3,5-diacetate; Methyl 2-deoxy-2-C-trifluoromethyl-α-D-ribofuranoside 3,5-diacetate; 159944-99-7; Fluorinated ribose derivative
EINECS	Contact for details

Quality Control

Our Methyl-2-C-(Trifluoromethyl)-α-D-Ribofuranoside-3,5-Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances, supporting its use in cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.