Description

(2-Boc-Aminophenyl)Boronic Acid, Pinacol Ester is a high-purity, protected boronic ester building block essential for modern synthetic chemistry. This compound is a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily used by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key protected precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant boronic ester reagent for palladium-catalyzed carbon-carbon bond formation.
• Medicinal Chemistry & Library Synthesis: Enables the rapid and efficient construction of diverse compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Advanced Material Synthesis: A building block for creating organic electronic materials, ligands for catalysts, and functional polymers.
• Peptide Modification & Bioconjugation: Facilitates the site-specific introduction of boron-containing groups into peptides and other biomolecules.

Basic Information

Product Name	(2-Boc-Aminophenyl)Boronic Acid, Pinacol Ester
CAS No.	159624-15-4
Molecular Formula	C₁₇H₂₆BNO₄
Molecular Weight	319.21 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)phenylboronic acid pinacol ester; 2-(Boc-amino)phenylboronic acid pinacol ester; N-Boc-2-aminophenylboronic acid pinacol ester; (2-((tert-Butoxycarbonyl)amino)phenyl)boronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-[2-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-4,4,5,5-tetramethyl-; tert-Butyl (2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate; BOC-2-Aminophenylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our (2-Boc-Aminophenyl)Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.