Description

3-Furancarboxaldehyde, Tetrahydro-2,5-Dimethoxy-, [2R-(2Alpha,3Beta,5Beta)]- (9Ci) is a high-purity, stereochemically defined furan derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique tetrahydrofuran core with methoxy and aldehyde functionalities makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and neurological drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its specific stereochemistry can influence biological activity and environmental profile.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, fragrances, and advanced materials requiring a defined tetrahydrofuran scaffold.
• Academic & Industrial Research: A valuable reagent in methodological chemistry research, including asymmetric synthesis, catalysis studies, and the development of new synthetic pathways.
• Ligand and Catalyst Development: The aldehyde group and chiral centers make it a precursor for novel chiral ligands and organocatalysts used in enantioselective transformations.

Basic Information

Product Name	3-Furancarboxaldehyde, Tetrahydro-2,5-Dimethoxy-, [2R-(2Alpha,3Beta,5Beta)]- (9Ci)
CAS No.	159551-33-4
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	(2R,3S,5R)-2,5-Dimethoxytetrahydrofuran-3-carbaldehyde; (2R,3S,5R)-2,5-Dimethoxy-3-tetrahydrofuraldehyde; Tetrahydro-2,5-dimethoxy-3-furancarboxaldehyde, (2R,3S,5R)-; 3-Formyl-2,5-dimethoxytetrahydrofuran (specifying [2R-(2α,3β,5β)]- isomer); (2R,3S,5R)-2,5-Dimethoxy-3-formyltetrahydrofuran; [2R-(2Alpha,3Beta,5Beta)]-Tetrahydro-2,5-dimethoxy-3-furancarboxaldehyde; 159551-33-4; THF-3-carboxaldehyde derivative
EINECS	Contact for details

Quality Control

Our 3-Furancarboxaldehyde, Tetrahydro-2,5-Dimethoxy-, [2R-(2Alpha,3Beta,5Beta)]- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.