Description

3-Furancarboxaldehyde, Tetrahydro-2,5-Dimethoxy-, [2S-(2Alpha,3Alpha,5Beta)]- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical sector where precise stereochemistry is critical for biological activity. It is needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting complex molecular architectures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the furan moiety and specific stereochemistry can influence biological activity and selectivity.
• Asymmetric Synthesis: Serves as a valuable starting material or intermediate in catalytic asymmetric reactions to construct other chiral molecules with high enantiomeric purity.
• Flavor & Fragrance Chemistry: Potential use as a precursor for synthesizing specific aroma compounds, leveraging the tetrahydrofuran scaffold.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies in organic synthesis and the exploration of new chemical spaces.
• Material Science Precursor: Can be utilized in the synthesis of specialized polymers or ligands for catalytic systems.

Basic Information

Product Name	3-Furancarboxaldehyde, Tetrahydro-2,5-Dimethoxy-, [2S-(2Alpha,3Alpha,5Beta)]- (9Ci)
CAS No.	159551-32-3
Molecular Formula	C8H14O4
Molecular Weight	174.19 g/mol
Synonyms	(2S,3S,5S)-Tetrahydro-2,5-dimethoxy-3-furancarboxaldehyde; (2S,3S,5S)-2,5-Dimethoxytetrahydro-3-furaldehyde; [2S-(2α,3α,5β)]-Tetrahydro-2,5-dimethoxy-3-furancarboxaldehyde; Tetrahydro-2,5-dimethoxy-3-furaldehyde (stereoisomer); 3-Formyl-2,5-dimethoxytetrahydrofuran (specific enantiomer); Chiral THF aldehyde derivative; 159551-32-3; (2S,3S,5S)-2,5-Dimethoxy-3-formyltetrahydrofuran
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 3-Furancarboxaldehyde, Tetrahydro-2,5-Dimethoxy-, [2S-(2Alpha,3Alpha,5Beta)]- (9Ci) is characterized and controlled using advanced analytical techniques to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) providing detailed specifications for chiral purity (enantiomeric excess), chemical purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This compound is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be kept tightly sealed and opened under controlled conditions to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.