Description

1H-Indene-1-Carboxaldehyde, 2,3-Dihydro-, (+)- (9Ci) is a chiral, optically active aldehyde derivative of indane, serving as a valuable and versatile building block in advanced organic synthesis. Its defined stereochemistry and reactive aldehyde group make it a critical intermediate for constructing complex molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients, chiral ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Chiral Ligand & Catalyst Development: Serves as a starting material for creating novel chiral auxiliaries, ligands for asymmetric catalysis, and organocatalysts.
• Fine Chemical & Specialty Material Production: Employed in the manufacture of advanced polymers, liquid crystals, and other functional materials requiring precise molecular architecture.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in organic chemistry, including new asymmetric synthesis routes and reaction development.

Basic Information

Product Name	1H-Indene-1-Carboxaldehyde, 2,3-Dihydro-, (+)- (9Ci)
CAS No.	159496-97-6
Molecular Formula	C10H10O
Molecular Weight	146.19 g/mol
Synonyms	(+)-2,3-Dihydro-1H-indene-1-carboxaldehyde; (1R)-2,3-Dihydro-1H-indene-1-carbaldehyde; (R)-(+)-Indane-1-carboxaldehyde; (R)-Indane-1-carbaldehyde; (R)-1-Formylindane; (R)-1-Indanecarboxaldehyde; (+)-1-Indanecarbaldehyde; (R)-(+)-1-Indanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our production of 1H-Indene-1-Carboxaldehyde, 2,3-Dihydro-, (+)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess (ee), and impurity profile is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature and reactive aldehyde group, prolonged exposure to light, air, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.