Description

Methyl 4-Chloro-2-Fluoro-3-(Methylthio)Benzoate is a high-purity, multi-functional aromatic ester building block designed for advanced chemical synthesis. This compound is valued for its unique halogenated and thioether-substituted benzoate structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting specific receptor sites where halogen and sulfur functionalities are critical.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the chloro-fluoro-methylthio motif.
• Material Science Research: Used in the development of specialty polymers and liquid crystals, where its aromatic core and substituents influence material properties.
• Organic Synthesis Reagent: Functions as a versatile electrophile or coupling partner in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce complex benzoate fragments.
• Chemical Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in related chemical production.

Basic Information

Item	Details
Product Name	Methyl 4-Chloro-2-Fluoro-3-(Methylthio)Benzoate
CAS No.	159329-14-3
Molecular Formula	C9H8ClFO2S
Molecular Weight	234.67 g/mol
Synonyms	Methyl 4-chloro-2-fluoro-3-(methylsulfanyl)benzoate; 4-Chloro-2-fluoro-3-(methylthio)benzoic acid methyl ester; Benzoic acid, 4-chloro-2-fluoro-3-(methylthio)-, methyl ester; Methyl 4-chloro-2-fluoro-3-methylthiobenzoate; 3-(Methylthio)-4-chloro-2-fluorobenzoic Acid Methyl Ester; CAS 159329-14-3
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Chloro-2-Fluoro-3-(Methylthio)Benzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.