Description

Benzoic Acid, 4-Borono-, 1-(2,5-Dioxo-1-Pyrrolidinyl) Ester is a specialized boronic acid derivative that serves as a crucial building block in advanced organic synthesis. Its core value lies in its dual functionality, combining a reactive boronic acid group with an activated ester, making it an efficient reagent for cross-coupling reactions and bioconjugation. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for boron-containing drugs.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds in the production of complex organic molecules.
• Bioconjugation & Probe Synthesis: Used for labeling biomolecules (proteins, antibodies) and creating diagnostic or imaging probes.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and insecticides.
• Material Science: Precursor for synthesizing boron-doped polymers and advanced functional materials.
• Chemical Biology: Tool compound for studying enzyme inhibition and protein-ligand interactions.

Basic Information

Product Name	Benzoic Acid, 4-Borono-, 1-(2,5-Dioxo-1-Pyrrolidinyl) Ester
CAS No.	159276-65-0
Molecular Formula	C13H12BNO6
Molecular Weight	289.05 g/mol
Synonyms	4-Boronobenzoic Acid N-Hydroxysuccinimide Ester; 4-Carboxyphenylboronic Acid NHS Ester; 4-Boronobenzoyloxysuccinimide; 4-(Hydroxycarbonyl)phenylboronic Acid N-Succinimidyl Ester; 4-Boronobenzoic Acid Succinimidyl Ester; B-4-(N-Succinimidyloxycarbonyl)phenylboronic Acid; 4-(2,5-Dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Borono-, 1-(2,5-Dioxo-1-Pyrrolidinyl) Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO; sparingly soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.