Description

3-Amino-3-(4-(tert-Butyl)Phenyl)Propan-1-Ol is a versatile chiral amino alcohol building block with significant synthetic utility. Its molecular structure, featuring both amino and hydroxyl functional groups on a propanol backbone attached to a sterically hindered aromatic ring, makes it a valuable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical developers engaged in asymmetric synthesis and medicinal chemistry. Its application is critical for producing high-value fine chemicals and active pharmaceutical ingredients (APIs) where precise stereochemistry is required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel therapeutic agents, including potential CNS drugs and enzyme inhibitors.
• Asymmetric Catalyst Ligand: Serves as a precursor for synthesizing chiral ligands used in metal-catalyzed asymmetric reactions, such as hydrogenation and alkylation.
• Agrochemical Research: Building block for creating advanced, stereoselective pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Intermediate in the synthesis of specialty polymers and advanced organic materials requiring specific molecular architectures.
• Academic & R&D: Essential reagent for methodological studies in organic synthesis and for exploring new reaction pathways in university and industrial laboratories.

Basic Information

Product Name	3-Amino-3-(4-(tert-Butyl)Phenyl)Propan-1-Ol
CAS No.	159262-24-5
Molecular Formula	C₁₃H₂₁NO
Molecular Weight	207.31 g/mol
Synonyms	3-Amino-3-(4-tert-butylphenyl)-1-propanol; 3-Amino-3-(p-tert-butylphenyl)propan-1-ol; 1-Propanol, 3-amino-3-[4-(1,1-dimethylethyl)phenyl]-; 3-Amino-3-(4-tert-butylphenyl)propanol; (RS)-3-Amino-3-(4-tert-butylphenyl)propan-1-ol; 3-Amino-3-(4-tert-butylphenyl)propyl alcohol; β-Amino-β-(4-tert-butylphenyl)propanol
EINECS	Contact for details

Quality Control

Our production of 3-Amino-3-(4-(tert-Butyl)Phenyl)Propan-1-Ol adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess (where applicable), and impurity profiles. Our quality system is designed to support cGMP compliance for pharmaceutical applications and meets the rigorous standards required for advanced R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.