Description

2-(5-Chloropent-1-Ynyl)-4,4,5,5-Tetramethyl-(1,3,2) Dioxaborolane is a high-value organoboron building block, specifically a pinacol boronate ester, designed for advanced synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and materials science research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates through palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific boron-containing motifs.
• Material Science: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of bioconjugation reagents and probes for labeling and studying biological systems.
• Ligand & Catalyst Development: Utilized to construct complex, functionalized ligands for transition metal catalysts.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Item	Details
Product Name	2-(5-Chloropent-1-Ynyl)-4,4,5,5-Tetramethyl-(1,3,2) Dioxaborolane
CAS No.	159087-42-0
Molecular Formula	C11H18BClO2
Molecular Weight	228.52 g/mol
Synonyms	5-Chloro-1-pentynylboronic acid pinacol ester; (5-Chloropent-1-yn-1-yl)boronic acid pinacol ester; 2-(5-Chloro-1-pentyn-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Chloro-1-pentynyl-Bpin; 159087-42-0; Pinacol (5-chloropent-1-yn-1-yl)boronate
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Chloropent-1-Ynyl)-4,4,5,5-Tetramethyl-(1,3,2) Dioxaborolane undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive cross-coupling applications. Our quality management system ensures traceability and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.