Description

1H-1,2,3-Triazole-4-Carboxaldehyde, 1-(2-Hydroxyethyl)- (9Ci) is a versatile heterocyclic building block featuring both an aldehyde and a hydroxyethyl functional group on a triazole core. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antiviral, anticancer, and anti-inflammatory drug candidates, leveraging the triazole scaffold's bioisosteric properties.
• Agrochemical Synthesis: Used in creating novel fungicides, herbicides, and plant growth regulators where the triazole ring contributes to biological activity.
• Ligand and Chelator Development: The aldehyde and hydroxyl groups serve as handles for constructing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: A monomer for producing specialty polymers with tailored properties, such as adhesives, coatings, and functional resins.
• Bioconjugation and Probe Chemistry: The reactive aldehyde group is utilized for labeling biomolecules (proteins, antibodies) in diagnostic assay development.
• Organic Synthesis Reagent: Serves as a precursor for further chemical transformations to create libraries of triazole-based compounds for screening.

Basic Information

Product Name	1H-1,2,3-Triazole-4-Carboxaldehyde, 1-(2-Hydroxyethyl)- (9Ci)
CAS No.	158877-12-4
Molecular Formula	C5H7N3O2
Molecular Weight	141.13 g/mol
Synonyms	1-(2-Hydroxyethyl)-1H-1,2,3-triazole-4-carboxaldehyde; 1H-1,2,3-Triazole-4-carboxaldehyde, 1-(2-hydroxyethyl)-; 4-Formyl-1-(2-hydroxyethyl)-1,2,3-triazole; 1-(2-Hydroxyethyl)-1H-1,2,3-triazole-4-carbaldehyde; 1-(2-Hydroxyethyl)-4-formyl-1,2,3-triazole; 158877-12-4; 1-(2-Hydroxyethyl)-1,2,3-triazole-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1H-1,2,3-Triazole-4-Carboxaldehyde, 1-(2-Hydroxyethyl)- (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.