Description

6,7-Difluoroindoline-2,3-Dione is a high-purity fluorinated isatin derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic incorporation of fluorine atoms, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides where fluorine substitution enhances bioavailability and environmental stability.
• Organic Electronic Materials: Serves as a precursor for electron-deficient units in the synthesis of organic semiconductors and fluorophores for OLEDs and sensors.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Design: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.

Basic Information

Product Name	6,7-Difluoroindoline-2,3-Dione
CAS No.	158580-95-1
Molecular Formula	C8H3F2NO2
Molecular Weight	183.11 g/mol
Synonyms	6,7-Difluoro-1H-indole-2,3-dione; 6,7-Difluoro-2,3-dioxoindoline; 6,7-Difluoro-2,3-dihydro-1H-indole-2,3-dione; 6,7-Difluoro-1H-indole-2,3(2H,3H)-dione; 6,7-Difluoro-isatin; 2,3-Dioxo-6,7-difluoroindoline; 6,7-Difluorooxindole-2,3-dione
EINECS	Contact for details

Quality Control

Our 6,7-Difluoroindoline-2,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.