Description

(R)-(+)-3,3-Difluoro-1,2-Heptanediol CAS NO 158358-96-4 is a high-value, chiral fluorinated diol building block. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research where the introduction of fluorine atoms and specific stereochemistry is essential for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel Active Pharmaceutical Ingredients (APIs), especially in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro moiety can enhance lipophilicity and biological efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Precursor: Employed in the synthesis of specialty polymers and liquid crystals, where fluorinated diols can impart unique thermal and surface properties.
• Chemical Biology Probes: Utilized in the creation of fluorinated probes and tags for studying biological mechanisms and enzyme interactions.
• Process Chemistry & Scale-up: Supports route scouting and optimization for the commercial-scale manufacturing of fluorinated fine chemicals.

Basic Information

Item	Detail
Product Name	(R)-(+)-3,3-Difluoro-1,2-Heptanediol
CAS No.	158358-96-4
Molecular Formula	C7H12F2O2
Molecular Weight	166.17 g/mol
Synonyms	(R)-3,3-Difluoroheptane-1,2-diol; (3R)-3,3-Difluoro-1,2-heptanediol; (R)-(+)-3,3-Difluoroheptane-1,2-diol; 158358-96-4; (R)-3,3-Difluoro-1,2-heptanediol; (+)-(R)-3,3-Difluoroheptane-1,2-diol
EINECS	Contact for details

Quality Control

Our (R)-(+)-3,3-Difluoro-1,2-Heptanediol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.