Description

4H-Pyran-4-One, Tetrahydro-3-(Trifluoroacetyl)- (9Ci) is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoroacetyl-substituted pyranone structure, which serves as a key precursor for synthesizing complex molecules with tailored properties. Pharmaceutical, agrochemical, and advanced material research and development teams need it to create novel active ingredients and functional materials where the introduction of fluorine atoms is critical for enhancing metabolic stability, bioavailability, or material performance.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases where fluorination is a key strategy.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoroacetyl group to improve product efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or intermediate in the production of specialty polymers, liquid crystals, and organic electronic materials that require specific fluorine-containing motifs for desired electronic or surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies in heterocyclic and fluorine chemistry, enabling the discovery of new synthetic routes and reactions.
• Fluorine-Containing Fine Chemical: Acts as a starting material for the preparation of other high-value, fluorinated fine chemicals and complex ligands used in catalysis.

Basic Information

Product Name	4H-Pyran-4-One, Tetrahydro-3-(Trifluoroacetyl)- (9Ci)
CAS No.	158351-87-2
Molecular Formula	C7H7F3O3
Molecular Weight	196.13 g/mol
Synonyms	3-(Trifluoroacetyl)-4H-pyran-4-one, tetrahydro-; Tetrahydro-3-(trifluoroacetyl)-4H-pyran-4-one; 4H-Pyran-4-one, tetrahydro-3-(trifluoroacetyl)-; 3-Trifluoroacetyl-4H-pyran-4-one, tetrahydro-; 3-(Trifluoroacetyl)dihydro-2H-pyran-4(3H)-one; 158351-87-2
EINECS	Contact for details

Quality Control

Our 4H-Pyran-4-One, Tetrahydro-3-(Trifluoroacetyl)- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, assay, and impurity profiles. For projects requiring specific regulatory support, we can discuss compliance with relevant frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); ensure containers are sealed after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.