Description

1-n-Boc-4-Aminomethyl-4-Phenylpiperidine is a high-purity, protected piperidine derivative used as a critical building block in advanced organic synthesis. This compound is essential for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences industry for the synthesis of novel active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of central nervous system (CNS) targeted drugs and other therapeutic agents.
• Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries in structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for candidate drugs during clinical development.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and mimetics due to its constrained piperidine structure.
• Chemical Biology: Acts as a functionalized linker or spacer in the synthesis of probes and tools for biological target identification and validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals for clients.

Basic Information

Product Name	1-n-Boc-4-Aminomethyl-4-Phenylpiperidine
CAS No.	158144-82-2
Molecular Formula	C17H26N2O2
Molecular Weight	290.41 g/mol
Synonyms	1-Boc-4-(Aminomethyl)-4-phenylpiperidine; tert-Butyl 4-(aminomethyl)-4-phenylpiperidine-1-carboxylate; 4-(Aminomethyl)-4-phenylpiperidine-1-carboxylic acid tert-butyl ester; 4-Phenyl-4-(aminomethyl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(aminomethyl)-4-phenylpiperidine; 1-(tert-Butoxycarbonyl)-4-(aminomethyl)-4-phenylpiperidine; 4-(Aminomethyl)-1-N-Boc-4-phenylpiperidine
EINECS	Contact for details

Quality Control

Our 1-n-Boc-4-Aminomethyl-4-Phenylpiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.