Description

3-Bromo-5-Formylphenylboronic Acid is a versatile bifunctional aromatic boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl and a boronic acid group on a brominated benzene ring, makes it an indispensable reagent for constructing complex molecular architectures via cross-coupling and subsequent functional group transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require reliable, high-quality raw materials for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients and herbicides with specific targeting properties.
• Liquid Crystal & OLED Materials: Serves as a building block for constructing complex organic molecules used in electronic displays and lighting.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific chemical or physical properties through its reactive functional groups.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and sensors for biochemical research and diagnostics.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	3-Bromo-5-Formylphenylboronic Acid
CAS No.	157866-06-3
Molecular Formula	C7H6BBrO3
Molecular Weight	228.84 g/mol
Synonyms	(3-Bromo-5-formylphenyl)boronic acid; 5-Bromo-3-formylbenzeneboronic acid; 3-Formyl-5-bromophenylboronic acid; Boronic acid, B-(3-bromo-5-formylphenyl)-; 3-Bromo-5-formylbenzeneboronic acid; 3-Bromo-5-carboxaldehydephenylboronic acid; 5-Bromobenzene-1,3-dicarboxaldehyde boronic acid derivative
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements of advanced R&D and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.