Description

4-Penten-1-One, 2-Fluoro-4-Methyl-1-Phenyl- (9Ci) is a specialized fluorinated organic building block with a unique α,β-unsaturated ketone structure. This compound matters for its role as a key intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate this specific fluorinated scaffold into novel molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and target binding.
• Material Science Research: Acts as a monomer or precursor for developing specialty polymers, liquid crystals, and advanced organic electronic materials with tailored properties.
• Fluorination Chemistry Studies: Employed in academic and industrial R&D to study the effects of fluorine substitution on reaction pathways and molecular properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Penten-1-One, 2-Fluoro-4-Methyl-1-Phenyl- (9Ci)
CAS No.	157690-14-7
Molecular Formula	C12H13FO
Molecular Weight	192.23 g/mol
Synonyms	2-Fluoro-4-methyl-1-phenyl-4-penten-1-one; 1-Phenyl-2-fluoro-4-methyl-4-penten-1-one; 4-Penten-1-one, 2-fluoro-4-methyl-1-phenyl-; 2-Fluoro-4-methyl-1-phenylpent-4-en-1-one; (E/Z)-2-Fluoro-4-methyl-1-phenylpent-4-en-1-one; α-Fluoro-β-methylcinnamyl methyl ketone (informal); Fluorinated phenyl pentenone derivative
EINECS	Contact for details

Quality Control

Our 4-Penten-1-One, 2-Fluoro-4-Methyl-1-Phenyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong alkali and fluoride ions; keep away from incompatible materials. For long-term storage, consider an inert atmosphere (e.g., nitrogen or argon) to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.