Description

Disodium (2S,3R)-2-Hydroxy-3-Isobutylsuccinate is a high-purity, chiral organic salt with significant utility in advanced chemical synthesis. This compound serves as a critical chiral building block and intermediate for the production of sophisticated active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and specialty chemical sectors that require enantiomerically pure intermediates to develop novel therapeutics and high-value products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly in routes requiring stereochemical control.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Biochemical Research: Employed as a substrate or standard in enzymatic studies and metabolic pathway research.
• Catalyst and Ligand Preparation: Useful in the synthesis of chiral ligands for asymmetric catalysis.
• Process Chemistry: Valued in scale-up and optimization of manufacturing processes for chiral compounds.

Basic Information

Product Name	Disodium (2S,3R)-2-Hydroxy-3-Isobutylsuccinate
CAS No.	157604-22-3
Molecular Formula	C8H12Na2O5
Molecular Weight	242.16 g/mol
Synonyms	Disodium (2S,3R)-2-Hydroxy-3-(2-methylpropyl)butanedioate; (2S,3R)-2-Hydroxy-3-isobutylsuccinic Acid Disodium Salt; Disodium (2S,3R)-2-Hydroxy-3-isobutylsuccinate; (2S,3R)-HIBS Disodium Salt; L-threo-2-Hydroxy-3-isobutylsuccinic Acid Disodium Salt; Disodium (2S,3R)-2-Hydroxy-3-(2-methylpropyl)succinate; Butanedioic acid, 2-hydroxy-3-(2-methylpropyl)-, (2S,3R)-, disodium salt
EINECS	Contact for details

Quality Control

Our Disodium (2S,3R)-2-Hydroxy-3-Isobutylsuccinate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) documenting identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 2.0%
Residue on Ignition	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.