Description

Methyl 2-Bromo-2-Fluoropropanoate is a versatile fluorinated building block essential for advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the same carbon, makes it a critical reagent for introducing fluorinated motifs into complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides with enhanced metabolic stability and bioavailability.
• Material Science: Serves as a monomer or precursor for specialty polymers and coatings with unique surface properties.
• Fluorine Chemistry Research: An important reagent for studying nucleophilic substitution reactions and developing new fluorination methodologies.
• Peptide Mimetics: Employed to create fluorinated amino acid analogs for probing protein structure and function.
• Ligand and Catalyst Development: Used to synthesize fluorinated phosphines and other ligands for catalytic applications.

Basic Information

Product Name	Methyl 2-Bromo-2-Fluoropropanoate
CAS No.	157415-07-1
Molecular Formula	C4H6BrFO2
Molecular Weight	185.00 g/mol
Synonyms	2-Bromo-2-fluoropropanoic acid methyl ester; Methyl α-bromo-α-fluoropropionate; 2-Fluoro-2-bromopropionic acid methyl ester; Methyl 2-fluoro-2-bromopropanoate; Propanoic acid, 2-bromo-2-fluoro-, methyl ester; 157415-07-1; Methyl 2-bromo-2-fluoropropionate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-2-Fluoropropanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.