Description

6-(4-Fluorophenyl)Pyridine-2-Carbaldehyde is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, featuring both an aldehyde group and a fluorinated aromatic system, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials due to its conjugated structure.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-(4-Fluorophenyl)Pyridine-2-Carbaldehyde
CAS No.	157402-44-3
Molecular Formula	C₁₂H₈FNO
Molecular Weight	201.20 g/mol
Synonyms	2-Formyl-6-(4-fluorophenyl)pyridine; 6-(p-Fluorophenyl)-2-pyridinecarboxaldehyde; 4-Fluoro-2-pyridinylbenzaldehyde; 2-Pyridinecarboxaldehyde, 6-(4-fluorophenyl)-; 157402-44-3; 6-(4-Fluorophenyl)picolinaldehyde; p-Fluorophenylpicolinaldehyde
EINECS	Contact for details

Quality Control

Every batch of 6-(4-Fluorophenyl)Pyridine-2-Carbaldehyde is produced under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.