Description

2-Bromo-1-(2-Fluoro-4-Methoxyphenyl)Ethanone is a high-purity, halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, primarily serving as a key electrophilic intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and methoxy-substituted aromatic systems.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and ether functionalities.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Ligand Synthesis: Acts as a precursor for creating complex ligands used in catalysis and coordination chemistry.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2-Bromo-1-(2-Fluoro-4-Methoxyphenyl)Ethanone
CAS No.	157014-35-2
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-Bromo-2'-fluoro-4'-methoxyacetophenone; 2'-Fluoro-4'-methoxy-α-bromoacetophenone; 1-(2-Fluoro-4-methoxyphenyl)-2-bromoethanone; α-Bromo-2-fluoro-4-methoxyacetophenone; 2-Bromo-1-(2-fluoro-4-methoxyphenyl)ethan-1-one; Bromo(2-fluoro-4-methoxyphenyl)methanone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(2-Fluoro-4-Methoxyphenyl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.