Description

(9H-Fluoren-9-Yl)Methyl 2-Oxoethylcarbamate is a specialized carbamate derivative featuring a fluorenylmethyl (Fmoc) protecting group linked to a reactive 2-oxoethyl moiety. This compound is a critical intermediate in advanced organic synthesis, particularly valued for its role in constructing complex molecules with precise functional group control. It is primarily utilized by research institutions and pharmaceutical development companies engaged in peptide synthesis, medicinal chemistry, and the production of high-value fine chemicals.

Application

• Peptide Synthesis Intermediate: Serves as a key building block in solid-phase and solution-phase peptide synthesis, often for introducing specific side-chain functionalities.
• Pharmaceutical Research: Used in the development and scale-up of active pharmaceutical ingredients (APIs) and novel drug candidates requiring protected amine or carbonyl groups.
• Bioconjugation Chemistry: Acts as a linker or spacer molecule for attaching fluorescent probes, drugs, or other payloads to proteins, antibodies, or nanoparticles.
• Polymer Science: Employed in the synthesis of functionalized polymers and dendrimers with tailored chemical properties.
• Chemical Biology Tool: Utilized in probe development for studying enzyme activity or protein-protein interactions.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke organic compounds.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methyl 2-Oxoethylcarbamate
CAS No.	156939-62-7
Molecular Formula	C18H15NO4
Molecular Weight	309.32 g/mol
Synonyms	Fmoc-Glyoxylyl; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glyoxylic acid amide; 2-Oxo-N-[(9H-fluoren-9-ylmethoxy)carbonyl]acetamide; N-(9-Fluorenylmethoxycarbonyl)glyoxylamide; Fmoc-glyoxylamide; Glyoxylic acid, 2-[(9H-fluoren-9-ylmethoxy)carbonylamino]-; (Fmoc-amino)glyoxal
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl 2-Oxoethylcarbamate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is easily oxidized; for long-term storage, consider under an inert atmosphere such as argon or nitrogen. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.