Description

1-Bromo-4-Ethoxy-2,3-Difluorobenzene is a high-value, multi-functional aromatic building block characterized by its bromo, ethoxy, and difluoro substituents. This compound matters as a versatile intermediate for constructing complex molecules, offering multiple sites for selective chemical modification. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoro and ethoxy groups contribute to biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Polymer Monomer: Employed in the creation of specialty polymers with tailored thermal, optical, or surface properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination methodologies and aromatic substitution patterns.

Basic Information

Product Name	1-Bromo-4-Ethoxy-2,3-Difluorobenzene
CAS No.	156573-09-0
Molecular Formula	C8H7BrF2O
Molecular Weight	237.04 g/mol
Synonyms	4-Bromo-1-ethoxy-2,3-difluorobenzene; 2,3-Difluoro-4-bromophenetole; 1-Ethoxy-4-bromo-2,3-difluorobenzene; Benzene, 1-bromo-4-ethoxy-2,3-difluoro-; 156573-09-0; 4-Bromo-2,3-difluorophenetole
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Ethoxy-2,3-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.