Description

Cyclopentanecarboxylic Acid, 2-Amino-4-Hydroxy-, (1Alpha,2Alpha,4Alpha)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry is critical for efficacy.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new therapeutic agents, including potential antiviral, antibacterial, or enzyme-inhibiting drugs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides or herbicides where specific stereoisomers exhibit enhanced biological activity and selectivity.
• Asymmetric Catalysis Research: Serves as a starting material or ligand precursor in the development of new chiral catalysts for stereoselective reactions.
• Peptidomimetics & Drug Design: Incorporated into the backbone of peptide analogs to modulate stability, bioavailability, and receptor binding properties.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.
• Academic & Industrial R&D: Utilized in chemical biology and medicinal chemistry programs to explore new chemical spaces and structure-activity relationships (SAR).

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Amino-4-Hydroxy-, (1Alpha,2Alpha,4Alpha)- (9Ci)
CAS No.	156406-08-5
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(1α,2α,4α)-2-Amino-4-hydroxycyclopentanecarboxylic acid; (1R,2R,4R)-2-Amino-4-hydroxycyclopentane-1-carboxylic acid; trans-2-Amino-cis-4-hydroxycyclopentanecarboxylic acid; 2-Amino-4-hydroxycyclopentanecarboxylic acid (stereoisomer); AHPCA; Cyclopentane amino acid derivative; Chiral cyclopentane scaffold.
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarboxylic Acid, 2-Amino-4-Hydroxy-, (1Alpha,2Alpha,4Alpha)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and cGMP manufacturing. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. Our quality management system supports compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.