Description

6,7,8-Indolizinetriol, 1-Fluorooctahydro-, 1R-(1.Alpha.,6.Alpha.,7.Beta.,8.Alpha.,8A.Alpha.)- is a high-purity, stereochemically defined fluorinated indolizine derivative. This compound matters as a sophisticated chiral building block and key intermediate for advanced pharmaceutical and agrochemical research, enabling the synthesis of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of new drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, or insecticides, leveraging its unique fluorinated polycyclic structure.
• Asymmetric Synthesis: Utilized in catalytic and stoichiometric asymmetric reactions to construct complex molecular architectures due to its defined stereocenters.
• Biochemical Probe Development: Used in life sciences research to create molecular probes for studying enzyme mechanisms or biological pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, specialty chemicals.
• Academic & Institutional Research: A valuable compound for universities and research institutes exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	6,7,8-Indolizinetriol, 1-Fluorooctahydro-, 1R-(1.Alpha.,6.Alpha.,7.Beta.,8.Alpha.,8A.Alpha.)-
CAS No.	156198-81-1
Molecular Formula	C8H13FO3
Molecular Weight	176.19 g/mol
Synonyms	(1R,6R,7S,8R,8aR)-1-Fluorooctahydro-6,7,8-indolizinetriol; 1-Fluorooctahydro-6,7,8-indolizinetriol, (1R,6R,7S,8R,8aR)-; 1-Fluoro-1,2,3,5,6,7,8,8a-octahydro-6,7,8-indolizinetriol; (1R,6R,7S,8R,8aR)-1-Fluoro-1,2,3,5,6,7,8,8a-octahydroindolizine-6,7,8-triol; Fluorinated Indolizine Triol Derivative
EINECS	Contact for details

Quality Control

Our 6,7,8-Indolizinetriol, 1-Fluorooctahydro-, 1R-(1.Alpha.,6.Alpha.,7.Beta.,8.Alpha.,8A.Alpha.)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.