Description

Propanoic Acid, 2,2-Dimethyl-, Octahydro-7,8-Dihydroxy-1,6-Indolizinediyl Ester, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, high-purity indolizidine alkaloid derivative with significant potential in advanced organic synthesis and pharmaceutical research. Its intricate stereochemistry and functional groups make it a valuable chiral building block for the development of novel bioactive compounds. This specialized intermediate is primarily sought by research institutions and pharmaceutical R&D departments focused on medicinal chemistry, process development, and the synthesis of natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological or metabolic targets.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Natural Product Synthesis: Serves as a critical intermediate in the total or semi-synthesis of complex indolizidine and related alkaloid natural products.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient production of target molecules in pilot plants.
• Biochemical Research: Potential use as a tool compound or probe for investigating specific enzymatic pathways or biological mechanisms.
• Advanced Material Science: May be utilized in the synthesis of specialized chiral ligands or catalysts for asymmetric synthesis.

Basic Information

Product Name	Propanoic Acid, 2,2-Dimethyl-, Octahydro-7,8-Dihydroxy-1,6-Indolizinediyl Ester, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156150-85-5
Molecular Formula	C13H23NO4
Molecular Weight	257.33 g/mol
Synonyms	(1S,6R,7S,8R,8aR)-Octahydro-7,8-dihydroxy-1,6-indolizinediyl 2,2-dimethylpropanoate; 1S-(1α,6β,7α,8β,8aβ)-Octahydro-7,8-dihydroxy-1,6-indolizinediyl Pivalate; Pivalic Acid, Octahydro-7,8-dihydroxy-1,6-indolizinediyl Ester, (1S,6R,7S,8R,8aR)-; Indolizidine Alkaloid Derivative; 2,2-Dimethylpropanoic Acid Octahydro-7,8-dihydroxy-1,6-indolizinediyl Ester; (1S,6R,7S,8R,8aR)-1,6-Indolizidinediyl Di-2,2-dimethylpropanoate (7,8-dihydroxyoctahydro-); 156150-85-5; Stereoisomer of Swainsonine Derivative
EINECS	Contact for details

Quality Control

Our high-purity research-grade material is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity, stereochemical purity, and chemical purity. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.