Description

5-Bromo-2-Methylbenzonitrile is a versatile brominated aromatic nitrile compound, serving as a critical building block in advanced organic synthesis. Its molecular structure makes it an essential intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This high-purity intermediate is primarily sought by research institutions and manufacturers engaged in creating active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Research: A valuable reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyano group transformations in academic and industrial R&D.
• Material Science: Employed in the synthesis of polymers and advanced organic materials with specific electronic or structural properties.
• Dye & Pigment Intermediate: Acts as a building block for creating complex colorants and functional dyes.

Basic Information

Product Name	5-Bromo-2-Methylbenzonitrile
CAS No.	156001-51-3
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	2-Methyl-5-bromobenzonitrile; 5-Bromo-o-tolunitrile; 5-Bromo-2-methylbenzenecarbonitrile; 2-Cyano-4-bromotoluene; 4-Bromo-2-cyanotoluene; Benzonitrile, 5-bromo-2-methyl-; 156001-51-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methylbenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 70 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.