Description

4-Bromo-4,4-Difluoro-1-Butanol is a versatile fluorinated and brominated organic building block with the CAS number 155957-60-1. This bifunctional compound is valued for its unique reactivity, serving as a key intermediate in the synthesis of complex molecules where the introduction of fluorine and bromine atoms is critical. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine and bromine functional groups into polymer chains, altering surface properties and chemical resistance.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating specialized chemical libraries.

Basic Information

Product Name	4-Bromo-4,4-Difluoro-1-Butanol
CAS No.	155957-60-1
Molecular Formula	C4H7BrF2O
Molecular Weight	189.00 g/mol
Synonyms	4-Bromo-4,4-difluorobutan-1-ol; 1-Butanol, 4-bromo-4,4-difluoro-; 4,4-Difluoro-4-bromo-1-butanol; 4-Bromo-4,4-difluorobutanol; 155957-60-1; 4-Bromo-4,4-difluorobutyl alcohol
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-4,4-Difluoro-1-Butanol is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency for research and production applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee reliable performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.