Description

2-(2H-Tetrazol-5-Yl)-Phenylboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, combining a tetrazole heterocycle with a phenylboronic acid moiety, makes it an invaluable reagent for constructing complex molecular architectures, particularly in pharmaceutical research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions and as a precursor for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting cardiovascular and central nervous system diseases.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl systems, which are common scaffolds in medicinal chemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the tetrazole ring.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its conjugated system.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and labeling strategies, exploiting the boronic acid group's affinity for diols.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in hit identification and lead optimization.

Basic Information

Product Name	2-(2H-Tetrazol-5-Yl)-Phenylboronic Acid
CAS No.	155884-01-8
Molecular Formula	C8H7BN4O2
Molecular Weight	202.98 g/mol
Synonyms	[2-(2H-Tetrazol-5-yl)phenyl]boronic acid; 2-(1H-Tetrazol-5-yl)benzeneboronic acid; 2-(2H-Tetrazol-5-yl)benzeneboronic acid; 2-(Tetrazol-5-yl)phenylboronic acid; 5-(2-Boronophenyl)-1H-tetrazole; 2-(1H-Tetrazol-5-yl)phenylboronic Acid; 2-(2H-1,2,3,4-Tetrazol-5-yl)phenylboronic acid; B-[2-(2H-Tetrazol-5-yl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(2H-Tetrazol-5-Yl)-Phenylboronic Acid is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical research and production processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.