Description

2-Propanone, 1-Fluoro-1-(2-Pyridinyl)- is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a pyridine ring and a fluorine atom adjacent to the carbonyl, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel pyridine-containing ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials due to its electron-deficient aromatic system.
• Fluorine Chemistry Research: An important building block for studying the effects of fluorine introduction on molecular conformation and reactivity in heterocyclic systems.

Basic Information

Product Name	2-Propanone, 1-Fluoro-1-(2-Pyridinyl)-
CAS No.	155794-57-3
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	1-Fluoro-1-(pyridin-2-yl)propan-1-one; 2-Acetylpyridine, α-fluoro-; 1-(2-Pyridinyl)-1-fluoropropanone; α-Fluoro-2-acetylpyridine; 2-Propanone, 1-fluoro-1-(2-pyridinyl)-; 1-Fluoro-1-(2-pyridyl)propan-1-one; 2-(1-Fluoropropan-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1-Fluoro-1-(2-Pyridinyl)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and relevant physical data is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0% (Research Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.