Description

Ethanone, 2,2,2-Trifluoro-1-[3-(1-Methylethyl)Phenyl]- (9Ci) is a specialized trifluoromethyl ketone derivative, a key structural motif valued for its unique electronic and steric properties. This compound matters as a high-value building block and intermediate in advanced organic synthesis, particularly where the introduction of a trifluoroacetyl group is required. It is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a key component in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials to modify solubility and electronic properties.
• Chemical Biology Probes: Utilized as a building block for creating activity-based probes and enzyme inhibitors to study biochemical pathways.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-[3-(1-Methylethyl)Phenyl]- (9Ci)
CAS No.	155628-02-7
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	1-[3-Isopropylphenyl]-2,2,2-trifluoroethanone; 3-Isopropyl-α,α,α-trifluoroacetophenone; 2,2,2-Trifluoro-1-(3-isopropylphenyl)ethanone; 3-Isopropyltrifluoroacetophenone; α,α,α-Trifluoro-3'-isopropylacetophenone; TFIPA; 1-(3-Isopropylphenyl)-2,2,2-trifluoro-1-ethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-[3-(1-Methylethyl)Phenyl]- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.