Description

5-(2-Iodophenyl)-5-Oxovaleronitrile is a versatile iodinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitrile group and a reactive iodophenyl moiety, makes it a valuable precursor for constructing complex heterocycles and functionalized intermediates. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Material Science: Employed in the research and development of organic electronic materials and liquid crystals.
• Chemical Biology: Acts as a building block for probes and tags used in bio-conjugation and imaging studies.
• Custom Synthesis: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.

Basic Information

Product Name	5-(2-Iodophenyl)-5-Oxovaleronitrile
CAS No.	155589-54-1
Molecular Formula	C11H8INO
Molecular Weight	297.09 g/mol
Synonyms	5-(2-Iodobenzoyl)valeronitrile; 4-Cyano-1-(2-iodophenyl)-1-butanone; 5-Oxo-5-(2-iodophenyl)pentanenitrile; 2-Iodophenyl 4-cyanobutyl ketone; δ-Oxo-δ-(2-iodophenyl)valeronitrile; 1-(2-Iodophenyl)-5-oxopentanenitrile; 155589-54-1
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Iodophenyl)-5-Oxovaleronitrile is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.