Description

2-Naphthalenecarboxaldehyde, 1,2,3,4-Tetrahydro-, (-)- (9Ci) is a chiral, tetrahydro-naphthalene-based aldehyde derivative. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the construction of complex molecules with defined stereochemistry. It is essential for research and development in the pharmaceutical and fine chemical industries, where precise control over molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to introduce the tetralin scaffold with high enantiomeric purity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in stereoselective transformations.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, including fragrances, agrochemicals, and advanced materials.
• Academic and R&D: Used in research laboratories for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	2-Naphthalenecarboxaldehyde, 1,2,3,4-Tetrahydro-, (-)- (9Ci)
CAS No.	155566-56-6
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	(-)-1,2,3,4-Tetrahydro-2-naphthaldehyde; (S)-1,2,3,4-Tetrahydro-2-naphthaldehyde; (2S)-1,2,3,4-Tetrahydronaphthalene-2-carboxaldehyde; 1,2,3,4-Tetrahydro-2-naphthalenecarboxaldehyde, (-)-; Tetralin-2-carboxaldehyde, (-)-; 2-Formyl-1,2,3,4-tetrahydronaphthalene, (S)-; Chiral Tetralin-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Naphthalenecarboxaldehyde, 1,2,3,4-Tetrahydro-, (-)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.