Description

Cyclopropanecarboxaldehyde, 2-(Dimethoxymethyl)-, trans- (9Ci) is a specialized chiral aldehyde building block featuring a cyclopropane ring and an acetal-protected aldehyde group. This compound matters as a high-value intermediate for the synthesis of complex, biologically active molecules, offering a rigid, three-dimensional scaffold that is crucial in modern medicinal chemistry. It is primarily needed by pharmaceutical R&D and process chemistry teams for constructing novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique structural properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological pathways and protein interactions.
• Flavor and Fragrance Chemistry: Potential intermediate for synthesizing complex aroma chemicals with unique olfactory profiles.

Basic Information

Item	Details
Product Name	Cyclopropanecarboxaldehyde, 2-(Dimethoxymethyl)-, trans- (9Ci)
CAS No.	155443-40-6
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	trans-2-(Dimethoxymethyl)cyclopropanecarboxaldehyde; (1R,2S)-rel-2-[(Dimethoxymethyl)cyclopropanecarbaldehyde; 2-(Dimethoxymethyl)cyclopropanecarbaldehyde (trans-); Cyclopropanecarboxaldehyde, 2-(dimethoxymethyl)-, (1R,2S)-rel-; (1R,2S)-2-(Dimethoxymethyl)cyclopropane-1-carbaldehyde; (1R,2S)-rel-2-(Dimethoxymethyl)cyclopropanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxaldehyde, 2-(Dimethoxymethyl)-, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans- isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.