Description

4-Amino-5-Bromo-2-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional aromatic intermediate featuring amino, bromo, cyano, and trifluoromethyl substituents. This compound is critical for its role as a versatile building block in advanced organic synthesis, enabling the introduction of key functional groups that modulate the biological activity and physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold for designing molecular probes, enzyme inhibitors, and labeled compounds for biochemical assays.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Amino-5-Bromo-2-(Trifluoromethyl)Benzonitrile
CAS No.	155255-45-1
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.03 g/mol
Synonyms	5-Bromo-4-amino-2-(trifluoromethyl)benzonitrile; 2-Cyano-5-bromo-4-aminobenzotrifluoride; 4-Amino-5-bromo-α,α,α-trifluoro-o-tolunitrile; 2-Amino-6-bromo-3-cyano-α,α,α-trifluorotoluene; Benzonitrile, 4-amino-5-bromo-2-(trifluoromethyl)-; 155255-45-1; 4-Amino-5-bromo-2-trifluoromethylbenzonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Bromo-2-(Trifluoromethyl)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.