Description

trans-2-(3,5-Difluorophenyl)-5-Propyl-1,3-Dioxane is a specialized fluorinated dioxane derivative, serving as a crucial advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis. Its unique structure, featuring a 1,3-dioxane ring and a difluorophenyl moiety, makes it an essential precursor for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This high-purity compound is primarily utilized by pharmaceutical R&D teams and custom synthesis providers focused on creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the difluorophenyl group can contribute to improved efficacy and environmental profile.
• Material Science: Serves as a monomer or precursor for synthesizing specialty polymers and advanced materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Employed in the design of chiral ligands and organocatalysts for asymmetric synthesis, leveraging the stereogenic center of the dioxane ring.
• Fluorine Chemistry Studies: Acts as a model compound in academic and industrial research exploring the effects of fluorine substitution on chemical reactivity and physical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for client projects.

Basic Information

Product Name	trans-2-(3,5-Difluorophenyl)-5-Propyl-1,3-Dioxane
CAS No.	155134-98-8
Molecular Formula	C13H16F2O2
Molecular Weight	242.26 g/mol
Synonyms	5-Propyl-2-(3,5-difluorophenyl)-1,3-dioxane (trans-); trans-5-Propyl-2-(3,5-difluorophenyl)-1,3-dioxane; 2-(3,5-Difluorophenyl)-5-propyl-1,3-dioxane; 1,3-Dioxane, 2-(3,5-difluorophenyl)-5-propyl-, trans-; (trans)-2-(3,5-Difluorophenyl)-5-propyl-1,3-dioxane; 155134-98-8; SCHEMBL2354541; DTXSID60674491
EINECS	Contact for details

Quality Control

Our trans-2-(3,5-Difluorophenyl)-5-Propyl-1,3-Dioxane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as identity, assay, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material suitable for advanced R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.